Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Antibody (APC)
689€ (100 tests)
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935106861
info@markelab.com
name
Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx270719
tested applications
FCM
Description
Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Antibody (APC) is a Rabbit Polyclonal Antibody conjugated to APC against Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) for use in flow cytometry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | APC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. |
| Dry Ice | No |
| Alias | Leukocyte immunoglobulin-like receptor subfamily A member 3,HM31,HM43,ILT6,LIR4,CD85E,ILT-6,LIR-4,Immunoglobulin-like transcript 6,Leukocyte immunoglobulin-like receptor 4,Monocyte inhibitory receptor HM43/HM31 |
| Background | Antibody anti-LILRA3 |
| Status | RUO |
Descripción
LILRA3 (Leukocyte Immunoglobulin-Like Receptor A3), also referred to as ILT6 or CD85e, is an intriguing member of the leukocyte immunoglobulin-like receptor (LILR) family, which is predominantly expressed on immune cells. LILRA3 is unique among LILR family members because it lacks a transmembrane domain, functioning as a soluble molecule. Found within the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, LILRA3 plays a significant role in modulating immune responses, particularly in inflammatory pathways. As a soluble receptor, LILRA3 is capable of binding various ligands, which include MHC class I molecules, and thus can modulate signaling pathways related to immune tolerance and immune response activation. Its specific function in the immune system remains somewhat enigmatic, as both pro-inflammatory and inhibitory effects have been suggested. However, it is recognized as a key player in regulating inflammation and immune homeostasis, with particular relevance in autoimmune diseases, infections, and certain cancers
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