Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
LILRA4 Antibody is a Rabbit Polyclonal against LILRA4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P59901 |
| Gene ID | 23547 |
| NCBI Accession | NP_036408.4 |
| OMIM | 607517 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily A member 4,ILT7,CD85g,Immunoglobulin-like transcript 7 |
| Background | Antibody anti-LILRA4 |
| Status | RUO |
Descripción
LILRA4 (Leukocyte Immunoglobulin-Like Receptor A4), also known as ILT7 or CD85g, is a member of the leukocyte immunoglobulin-like receptor (LILR) family, which is primarily involved in modulating immune responses. This receptor family is part of the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, where several LILR family members are located, often associated with immune regulation. LILRA4 is distinct among LILRs as it is uniquely expressed on plasmacytoid dendritic cells (pDCs), a specialized dendritic cell subset primarily responsible for antiviral responses and producing type I interferons in response to viral infection. LILRA4 plays a suppressive role on pDCs by modulating interferon production, impacting immune responses, and helping maintain immune homeostasis. The regulation of interferon responses by LILRA4 is crucial, particularly because excessive interferon production can contribute to inflammatory and autoimmune disorders
Related Products
anti- LILRA4 antibody
May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4.
Ver Producto
Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) Antibody
LILRA4 Antibody is a Rabbit Polyclonal antibody against LILRA4. This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4.
Ver Producto
Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) Antibody
Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With Tm Domain), Member 4 Antibody is a Rabbit Polyclonal antibody against Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With Tm Domain), Member 4.
Ver Producto