Leucine-Rich Repeat-Containing Protein 3 (LRRC3) Antibody
357.5€ (100 µg)
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Name
Leucine-Rich Repeat-Containing Protein 3 (LRRC3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037241
Tested Applications
ELISA, IHC
Description
Rabbit Polyclonal against the LRRC3 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leucine-Rich Repeat-Containing Protein 3 (LRRC3) Immunogen: Recombinant fragment corresponding to 59-236 AA of human LRRC3. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 28 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | LRRC3, C21orf102, LRRC3A |
| Background | Antibody anti-LRRC3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
LRRC3 is a protein primarily associated with cellular signaling and cytoskeletal organization expressed in various tissues including muscle and epithelial cells it is thought to modulate cellular adhesion and migration processes by interacting with extracellular matrix components and actin-binding proteins studies suggest LRRC3 plays a role in tissue remodeling particularly during wound healing and epithelial-mesenchymal transition (EMT) its expression has been linked to cancer biology where it may influence tumor progression and metastasis through its effects on cell motility and invasion bioinformatics analyses associate LRRC3 with Wnt/β-catenin and MAPK signaling pathways indicating its potential involvement in regulating cellular proliferation and differentiation despite limited direct experimental evidence research is exploring its potential as a biomarker in cancer and fibrotic diseases further studies are needed to clarify its molecular mechanisms and therapeutic applications
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