Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025784
tested applications
ELISA, WB
Description
May be involved in the activation of cells of innate and acquired immunity.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine-Rich Repeat-Containing Protein 25 (LRRC25) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N386 |
| Alias | LRRC25,MAPA,Monocyte and plasmacytoid-activated protein |
| Background | Antibody anti-LRRC25 |
| Status | RUO |
Descripción
LRRC25 is an innate immune receptor predominantly expressed in neutrophils and macrophages where it plays a role in mediating the immune response against infections and cellular stress it functions as a regulator of toll-like receptor (TLR) and nuclear factor-kappa B (NF-κB) signaling pathways essential for pro-inflammatory cytokine production and pathogen clearance studies show that LRRC25 is involved in the recognition of damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) facilitating the recruitment of immune cells to sites of infection or injury it also participates in the regulation of neutrophil extracellular traps (NETs) which are critical in trapping and neutralizing pathogens dysregulated LRRC25 activity has been linked to chronic inflammatory diseases and autoimmune disorders ongoing research is investigating its potential role as a therapeutic target in modulating hyperactive inflammatory responses and its involvement in the crosstalk between innate and adaptive immunity
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