Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx025784
Tested Applications
ELISA, WB
Description
May be involved in the activation of cells of innate and acquired immunity.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Immunogen: KLH-conjugated synthetic peptide between 242-270 amino acids from the C-terminal region of human LRRC25. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 33.2 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N386 |
| Alias | LRRC25,MAPA,Monocyte and plasmacytoid-activated protein |
| Background | Antibody anti-LRRC25 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
LRRC25 is an innate immune receptor predominantly expressed in neutrophils and macrophages where it plays a role in mediating the immune response against infections and cellular stress it functions as a regulator of toll-like receptor (TLR) and nuclear factor-kappa B (NF-κB) signaling pathways essential for pro-inflammatory cytokine production and pathogen clearance studies show that LRRC25 is involved in the recognition of damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs) facilitating the recruitment of immune cells to sites of infection or injury it also participates in the regulation of neutrophil extracellular traps (NETs) which are critical in trapping and neutralizing pathogens dysregulated LRRC25 activity has been linked to chronic inflammatory diseases and autoimmune disorders ongoing research is investigating its potential role as a therapeutic target in modulating hyperactive inflammatory responses and its involvement in the crosstalk between innate and adaptive immunity
Productos relacionados
Leucine-Rich Repeat-Containing Protein 25 (LRRC25) Antibody
May be involved in the activation of cells of innate and acquired immunity.…
Ver producto
Human Leucine-rich repeat-containing protein 25 (LRRC25) ELISA Kit
Human Leucine-rich repeat-containing protein 25 (LRRC25) ELISA Kit is an ELISA Kit for the in vitro quantitative measure…
Ver producto Mouse Leucine-rich repeat-containing protein 25 (LRRC25) ELISA Kit
Mouse Leucine-rich repeat-containing protein 25 (LRRC25) ELISA Kit is an ELISA Kit for the in vitro quantitative measure…
Ver producto