Leucine Rich Repeat Containing 41 (LRRC41) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Leucine Rich Repeat Containing 41 (LRRC41) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014549
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against LRRC41 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leucine Rich Repeat Containing 41 (LRRC41) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15345 |
| Alias | LRRC41, MUF1, PP7759 |
| Background | Antibody anti-LRRC41 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
LRRC41 is a protein with proposed roles in DNA damage repair and ubiquitin-mediated proteolysis studies suggest it functions as an E3 ubiquitin ligase interacting with other proteins involved in the ubiquitin-proteasome system to regulate protein turnover and cellular stress responses LRRC41 is widely expressed in tissues undergoing high cellular turnover and is particularly enriched in hematopoietic cells where it may influence cell cycle progression and apoptosis its involvement in DNA repair pathways highlights its potential role in maintaining genomic stability and preventing tumorigenesis mutations or altered expression of LRRC41 have been associated with certain cancers and hematological disorders ongoing research is exploring its function in protein quality control and its potential as a therapeutic target in diseases associated with proteostasis and genomic instability further studies are needed to define its exact biological mechanisms and regulatory networks
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