Leucine Rich Repeat Containing 41 (LRRC41) Antibody
52€ (10 µg)
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Name
Leucine Rich Repeat Containing 41 (LRRC41) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx014549
Tested Applications
ELISA, WB
Description
Rabbit polyclonal antibody against LRRC41 protein. Immunogen region is Internal.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leucine Rich Repeat Containing 41 (LRRC41) Immunogen: The antiserum was produced against synthesized peptide derived from internal of human LRRC41. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15345 |
| Alias | LRRC41, MUF1, PP7759 |
| Background | Antibody anti-LRRC41 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
LRRC41 is a protein with proposed roles in DNA damage repair and ubiquitin-mediated proteolysis studies suggest it functions as an E3 ubiquitin ligase interacting with other proteins involved in the ubiquitin-proteasome system to regulate protein turnover and cellular stress responses LRRC41 is widely expressed in tissues undergoing high cellular turnover and is particularly enriched in hematopoietic cells where it may influence cell cycle progression and apoptosis its involvement in DNA repair pathways highlights its potential role in maintaining genomic stability and preventing tumorigenesis mutations or altered expression of LRRC41 have been associated with certain cancers and hematological disorders ongoing research is exploring its function in protein quality control and its potential as a therapeutic target in diseases associated with proteostasis and genomic instability further studies are needed to define its exact biological mechanisms and regulatory networks
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