LGALS3 Antibody is a Rabbit Polyclonal antibody against LGALS3. Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of ∫1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn’s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
Lectin-Galactoside Binding Soluble 3 (LGALS3)
Rabbit
Unconjugated
Liquid
WB, IF/ICC
Purified by affinity chromatography.
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
20 µl
50 µl
100 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
LGALS3
No
Shipped within 5-10 working days.
NP_002297.2
This product is for research use only.
Precio a consultar
Ver másPrecio a consultar
Ver másLGALS3 Antibody is a Rabbit Polyclonal antibody against LGALS3. Galectins are a family of soluble b-galactoside-binding ...
175€ (20 µl)
Ver más