LCK (pY505) Antibody
208€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
LCK (pY505) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000336
Tested Applications
ELISA, WB, IP
Description
LCK (pY505) Antibody is a Rabbit Polyclonal antibody against LCK (pY505). This gene is a member of the Src family of protein tyrosine kinases (pYKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: LCK (pY505) Immunogen: Synthetic peptide corresponding to LCK (pY505). The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 58 kDa Observed MW: 56 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IP |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P06239 |
| Gene ID | 3932 |
| NCBI Accession | NP_001036236.1 |
| Background | Antibody anti-LCK |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
LCK (pY394) Antibody
LCK (pY394) Antibody is a Rabbit Polyclonal antibody against LCK (pY394). This gene is a member of the Src family of pro…
Ver producto LCK (pY505) Antibody
LCK (pY505) Antibody is a Rabbit Polyclonal antibody against LCK (pY505). This gene is a member of the Src family of pro…
Ver producto
Proto-Oncogene Tyrosine-Protein Kinase LCK (LCK) Antibody
LCK Antibody is a Rabbit Polyclonal antibody against LCK. This gene is a member of the Src family of protein tyrosine ki…
Ver producto