L-Selectin / CD62L (SELL) Antibody

Este producto es parte de SELL - selectin L
Product Graph
364€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
L-Selectin / CD62L (SELL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx219084
tested applications
ELISA, WB, IHC, IF/ICC

Description

L-Selectin / CD62L (SELL) Antibody is a Rabbit Polyclonal antibody for the detection of L-Selectin.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
L-Selectin / CD62L (SELL)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P14151
Gene ID
6402
OMIM
153240
Alias
TQ1,LAM1,LEU8,LNHR,LSEL,CD62L,LYAM1,PLNHR,LECAM1,L-selectin,CD62 antigen-like family member L,Leukocyte adhesion molecule 1,Leukocyte surface antigen Leu-8,Leukocyte-endothelial cell adhesion molecule 1
Background
Antibody anti-SELL
Status
RUO
Note
Concentration: 2 mg/ml - Validity: 12 months.

Descripción

Selectin L (SELL), commonly known as L-selectin, is a cell adhesion molecule that belongs to the selectin family, which includes three primary members: L-selectin (SELL), E-selectin (SELE), and P-selectin (SELP). L-selectin plays a crucial role in immune surveillance and inflammatory responses, primarily facilitating the interaction between leukocytes (white blood cells) and endothelial cells. SELL is expressed constitutively on most leukocytes, including neutrophils, monocytes, T lymphocytes, B lymphocytes, and natural killer (NK) cells. It is essential for the initial steps of leukocyte extravasation, where leukocytes migrate from the bloodstream to peripheral tissues to respond to infection or injury. SELL mediates leukocyte rolling on the endothelium, an essential part of the immune cell recruitment cascade during inflammation and immune surveillance. It is involved in homing of lymphocytes to secondary lymphoid organs, such as lymph nodes, and facilitates the recruitment of leukocytes to sites of inflammation. SELL’s primary ligands include sialyl Lewis X (sLeX) and GlyCAM-1 (glycan-bearing cell adhesion molecule-1), which are expressed on endothelial cells. The role of L-selectin in trafficking leukocytes to lymphoid tissues is vital for maintaining immune homeostasis and responding to pathogens.

Related Products

APC-30084

APC Anti-Mouse CD62L Antibody(Mel14)

Ver Producto
APC-30091

APC Anti-Human CD62L Antibody(DREG56)

Ver Producto
EH3764

Human SELL (L-Selectin) ELISA Kit

Ver Producto