Krev interaction trapped protein 1 (KRIT1) Antibody

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Description
Krev interaction trapped protein 1 (KRIT1) Antibody is a Rabbit Polyclonal antibody for the detection of Human KRIT1.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Krev interaction trapped protein 1 (KRIT1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G chromatography. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O00522 |
Gene ID | 889 |
Background | Antibody anti-KRIT1 |
Status | RUO |
Descripción
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Krev Interaction Trapped Protein 1 (KRIT1) Antibody
KRIT1 Antibody is a Rabbit Polyclonal antibody against KRIT1. This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene.
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Krev interaction trapped protein 1 (KRIT1) Antibody
Krev interaction trapped protein 1 (KRIT1) Antibody is a Rabbit Polyclonal antibody for the detection of Human KRIT1.
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