935106861
info@markelab.com
Precio
400€ (100 tests)
Killer Cell Immunoglobulin-Like Receptor 2DL5A (KIR2DL5A) Antibody is a Mouse Monoclonal against Killer Cell Immunoglobulin-Like Receptor 2DL5A (KIR2DL5A).
Killer cell immunoglobulin-like receptor 2DL5A (KIR2DL5A) is a member of the KIR family, which plays a crucial role in immune regulation, especially in natural killer (NK) cell and some T-cell activities. These receptors allow immune cells to differentiate between normal cells and those that may be infected, stressed, or malignant. KIR2DL5A, like other inhibitory KIR receptors, is known for its role in maintaining immune tolerance by providing inhibitory signals to prevent NK cells from attacking healthy tissues. This regulation is achieved through interactions with specific ligands, mainly human leukocyte antigen (HLA) class I molecules on target cells. However, the specific HLA ligands for KIR2DL5A remain under research, with some studies suggesting unique ligand interactions within this receptor subtype. KIR2DL5A is located on chromosome 19 within the KIR gene cluster, which exhibits considerable genetic diversity across individuals. This diversity allows NK cells to adapt to various pathogenic and environmental pressures. The polymorphic nature of KIR genes like KIR2DL5A contributes to variations in immune responses between individuals, which can influence susceptibility to infections, autoimmune diseases, and cancer.
Primary Antibodies
Monoclonal
Human
Killer Cell Immunoglobulin-Like Receptor 2DL5A (KIR2DL5A)
Mouse
APC
FCM
Stabilizing PBS solution containing 15 mM sodium azide.
100 tests
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
KIR2DL5A
No
Shipped within 5-12 working days.
CD158F,KIR2DL5,KIR2DL5.1,KIR2DL5.3
This product is for research use only.
Rabbit polyclonal antibody against KIR2DL5B protein. Immunogen region is Internal.
43.75€ (10 µg)
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