Keratin, Type I Cytoskeletal 18 (KRT18) Antibody (Biotin)

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Description
Cytokeratin 18 Antibody is a Mouse Monoclonal against Cytokeratin 18.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | Keratin, Type I Cytoskeletal 18 (KRT18)  | 
| Host | Mouse  | 
| Reactivity | Human  | 
| Recommended Dilution | WB: 1-2 μg/ml, FCM: 2-6 μg/ml. Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Monoclonal  | 
| Conjugation | Biotin  | 
| Isotype | IgG1  | 
| Clone ID | N321  | 
| Size 1 | 0.1 mg  | 
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM, IP  | 
| Buffer | PBS solution with 15 mM sodium azide.  | 
| Availability | Shipped within 5-12 working days.  | 
| Storage | Store at 2-8°C. Do not freeze.  | 
| Dry Ice | No  | 
| UniProt ID | P05783  | 
| Gene ID | 3875  | 
| Background | Antibody anti-KRT18  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
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