Keratin 18 (KRT18) Antibody
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Description
CK18 Antibody is a Mouse Monoclonal antibody against Human, Mouse and Rat.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Keratin 18 (KRT18) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Validated in IHC-P and ICC. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Purification | Purified by Protein A or Protein G. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | TBS, pH 7.4, 0.5% BSA, 25% glycerol and 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5BJY9 |
| Gene ID | 294853 |
| Background | Antibody anti-KRT18 |
| Status | RUO |
Descripción
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Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
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