Katanin P80 WD40 Repeat-Containing Subunit B1 (KATNB1) Antibody
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Description
Katanin P80 WD40 Repeat-Containing Subunit B1 (KATNB1) Antibody is a Rabbit polyclonal antibody for the detection of Human Katanin P80 WD40 Repeat-Containing Subunit B1 (KATNB1).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Katanin P80 WD40 Repeat-Containing Subunit B1 (KATNB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BVA0 |
| Gene ID | 10300 |
| NCBI Accession | NP_005877.2 |
| Background | Antibody anti-KATNB1 |
| Status | RUO |
Descripción
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Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
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