Kallistatin (SERPINA4) Antibody
221€ (50 µg)
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Name
Kallistatin (SERPINA4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx323735
Tested Applications
ELISA, WB
Description
SERPINA4 Antibody is a Rabbit Polyclonal against SERPINA4.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Kallistatin (SERPINA4) Immunogen: Synthesized peptide derived from the Internal region of human Kallistatin. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29622 |
| Gene ID | 5267 |
| Alias | KAL,KST,PI4,KLST,PI-4,kallistatin,Kallikrein inhibitor,Peptidase inhibitor 4,Serpin A4 |
| Background | Antibody anti-SERPINA4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SERPINA4, also known as kallistatin, is a member of the serine protease inhibitor (serpin) superfamily, which plays a critical role in the regulation of various proteolytic processes in the body. This gene is located on chromosome 14q32.13, a region that houses a cluster of other serpin genes, including SERPINA1 and SERPINA3. Kallistatin was first identified as a potent inhibitor of tissue kallikrein, a serine protease involved in the generation of kinins, which are peptides that contribute to blood pressure regulation, inflammation, and pain. Kallistatin is synthesized primarily in the liver and circulates in the blood, but it is also expressed in other tissues, including the heart, kidneys, and vasculature. The protein encoded by SERPINA4 is involved in a wide range of physiological processes, including the regulation of blood pressure, angiogenesis, inflammation, and oxidative stress
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