Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody
![Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody](https://www.abbexa.com/image/cache/data/products/10A/abx033407_IDH1_Antibody_IF_1-180x180.jpg)
292.5€ (80 µl)
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Name
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx033407
Tested Applications
ELISA, WB, IHC, IF/ICC, FCM
Description
IDH1 belongs to two distinct subclasses. The protein is the NADP (+) dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) Immunogen: KLH-conjugated synthetic peptide between 116-143 amino acids from the Central region of human IDH1. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 46.7 kDa |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75874 |
| NCBI Accession | NP_001269315.1, NP_001269316.1, NP_005887.2 |
| Background | Antibody anti-IDH1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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