Islet Amyloid Polypeptide (IAPP) Antibody

Descripción

IAPP Antibody is a Rabbit Polyclonal antibody against IAPP. Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Islet Amyloid Polypeptide (IAPP)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

WB, IHC, IF/ICC

purification

Purified by affinity chromatography.

buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

size 1

20 µl

size 2

50 µl

size 3

100 µl

size 4

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

IAPP

dry ice

availability

Shipped within 5-10 working days.

alias

Amylin,IAP,Diabetes-Associated Peptide Diabetes-Associated Peptide

uniprot id

https://www.uniprot.org/uniprotkb/P10997

gene id

https://www.ncbi.nlm.nih.gov/gene/3375

NCBI accession

NP_000406.1

note

This product is for research use only.

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