Iron-Responsive Element-Binding Protein 2 (IREB2) Antibody

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260€ (50 µg)

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935106861
info@markelab.com
name
Iron-Responsive Element-Binding Protein 2 (IREB2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455403
tested applications
ELISA, WB, IHC

Description

Iron-Responsive Element-Binding Protein 2 (IREB2) Antibody is a Rabbit polyclonal antibody for the detection of Human Iron-Responsive Element-Binding Protein 2 (IREB2).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Iron-Responsive Element-Binding Protein 2 (IREB2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P48200
Gene ID
3658
NCBI Accession
NP_001307870.1
Background
Antibody anti-IREB2
Status
RUO

Descripción

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IREB2 antibody

RNA-binding protein that binds to iron-responsive elements(IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

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