IREB2 antibody
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935106861
info@markelab.com
name
IREB2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04384
tested applications
ELISA, WB, IF
Description
RNA-binding protein that binds to iron-responsive elements(IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | iron-responsive element binding protein 2 (IREB2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 90-105 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P48200 |
| Gene ID | 3658 |
| Alias | Iron-responsive element-binding protein 2 (IRE-BP 2),Iron regulatory protein 2 (IRP2),IREB2 |
| Background | Antibody anti-IREB2 |
| Status | RUO |
| Note | Mol. Weight 90-105 kDa |
Descripción
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IREB2 antibody
RNA-binding protein that binds to iron-responsive elements(IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Ver Producto