Intermediate Conductance Calcium-Activated Potassium Channel Protein 4 (KCNN4) Peptide
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Description
Intermediate Conductance Calcium-Activated Potassium Channel Protein 4 (KCNN4) Peptide is a synthetic peptide. This peptide is used in the production of
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Intermediate Conductance Calcium-Activated Potassium Channel Protein 4 (KCNN4) |
| Host | Synthetic |
| Assay Type | Activity: Not tested. Sequence Fragment: Internal region: C-ERQAVNATGHLSD |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 3783, 16534, 65206 |
| NCBI Accession | NP_002241.1 |
| Background | Protein KCNN4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water. |
Descripción
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Forms a voltage-independent potassium channel that is activated by intracellular calcium(PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin(PubMed:17157250, PubMed:18796614).
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KCNN4 Antibody is a Rabbit Polyclonal antibody against KCNN4. The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
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