Interferon Lambda-2 (IFNL2) Antibody Pair
1326€ (5 × 96 tests)
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935106861
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name
Interferon Lambda-2 (IFNL2) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370565
tested applications
ELISA
Description
Interferon Lambda-2 (IFNL2) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Detection: 50 µg Capture: 200 µg Standard: 2 µg
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Interferon Lambda-2 (IFNL2) |
| Reactivity | Human |
| Assay Data | Sandwich |
| Assay Type | Capture Antibody: 0.5 mg/ml Biotin-Conjugated Detection Antibody: 0.2 mg/ml Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. |
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Biotin |
| Size 1 | 5 × 96 tests |
| Size 2 | 10 × 96 tests |
| Form | Standard form: Lyophilized Capture Ab: Liquid Detection Ab: Liquid |
| Tested Applications | ELISA |
| Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide. |
| Availability | Shipped within 5-20 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | IL28B,IL28C,IL-28B,IL-28C,IFN-lambda-3,IFN-lambda-4,Cytokine Zcyto22,Interleukin-28B,Interleukin-28C |
| Background | Antibody pair for IFNL2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Interferon Lambda 3 (IFNL3), also known as IL-28B, is a cytokine that belongs to the Type III interferon family, which plays a critical role in the innate immune system, particularly in antiviral defense. IFNL3, like other Type III interferons, activates signaling pathways that result in the expression of interferon-stimulated genes (ISGs), creating an antiviral state within cells. IFNL3 primarily targets epithelial cells, such as those lining the respiratory tract, gastrointestinal tract, and liver, which are common entry points for viral infections. The discovery of IFNL3 and its genetic variations has been of significant interest, especially due to its role in the treatment and clearance of hepatitis C virus (HCV) infections. Genetic polymorphisms in the IFNL3 gene are strong predictors of treatment response in HCV patients, influencing outcomes of both spontaneous viral clearance and antiviral therapy. This connection has made IFNL3 a focus of research in viral infections, where immune response to chronic infections is crucial.
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