IL-28A antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
IL-28A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04262
tested applications
ELISA, WB, IHC
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interleukin 28A(interferon, lambda 2) (IL-28A) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1:5000-1:50000; IHC: 1:20-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 1H10 |
| Observed MW | 34 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IZJ0 |
| Gene ID | 282616 |
| Alias | IL28A,IFNL2a,IFNL3a,IFN-lambda-2,Cytokine Zcyto20,Interleukin-28A |
| Background | Antibody anti-IFNL2 |
| Status | RUO |
| Note | Mol. Weight 34 kDa |
Interferon Lambda 3 (IFNL3), also known as IL-28B, is a cytokine that belongs to the Type III interferon family, which plays a critical role in the innate immune system, particularly in antiviral defense. IFNL3, like other Type III interferons, activates signaling pathways that result in the expression of interferon-stimulated genes (ISGs), creating an antiviral state within cells. IFNL3 primarily targets epithelial cells, such as those lining the respiratory tract, gastrointestinal tract, and liver, which are common entry points for viral infections. The discovery of IFNL3 and its genetic variations has been of significant interest, especially due to its role in the treatment and clearance of hepatitis C virus (HCV) infections. Genetic polymorphisms in the IFNL3 gene are strong predictors of treatment response in HCV patients, influencing outcomes of both spontaneous viral clearance and antiviral therapy. This connection has made IFNL3 a focus of research in viral infections, where immune response to chronic infections is crucial.
Related Products
Human IL-28A (Interleukin-28A) ELISA Kit
Ver Producto
IL-28A antibody
Ver Producto