Interleukin 26 (IL26) Antibody
273€ (100 µl)
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935106861
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name
Interleukin 26 (IL26) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx177157
tested applications
WB, IHC, IF/ICC
Description
Interleukin 26 (IL26) Antibody is a Rabbit Polyclonal antibody against Interleukin 26 (IL26).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 26 (IL26) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AK155,IL-26,Protein AK155 |
| Background | Antibody anti-IL26 |
| Status | RUO |
Descripción
Interleukin 26 (IL26) is a member of the IL-10 cytokine family and is notable for its dual role in both immune modulation and antimicrobial defense. It is predominantly expressed by activated T cells, especially Th17 cells, as well as NK cells and some monocytes. IL-26 has been primarily studied in the context of chronic inflammation and is implicated in the pathogenesis of various autoimmune conditions, particularly rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and other chronic inflammatory diseases. IL-26 plays a unique role within the immune system by acting as both a cytokine and a host-defense peptide. As a cytokine, it helps orchestrate immune responses, particularly those involving Th17 cells, and as an antimicrobial peptide, it exhibits direct bactericidal properties. Its ability to bind and disrupt bacterial membranes marks IL-26 as part of the innate immune defense against pathogens.
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