Interleukin 23 (IL23) Antibody (Biotin)
351€ (200 µl)
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935106861
info@markelab.com
name
Interleukin 23 (IL23) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx271331
tested applications
WB, IHC, IF/ICC
Description
Interleukin 23 (IL23) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Interleukin 23 (IL23).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 23 (IL23) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | P19,SGRF,IL-23,L-23A,IL23P19,L-23 subunit alpha,IL-23-A,Interleukin-23 subunit p19 IL-23p19 |
| Background | Antibody anti-IL23A |
| Status | RUO |
| Note | Concentration: 0.35 mg/ml - |
Descripción
Interleukin 23A (IL23A), also referred to as IL-23, is a heterodimeric cytokine that plays a pivotal role in immune regulation, inflammation, and host defense. It is a member of the IL-12 cytokine family, which is integral to bridging the innate and adaptive immune systems. IL-23 is predominantly produced by antigen-presenting cells (such as dendritic cells and macrophages) and acts mainly on T cells, specifically promoting the differentiation, expansion, and maintenance of Th17 cells. IL-23 is essential for chronic inflammation and has been implicated in several autoimmune and inflammatory diseases, including psoriasis, rheumatoid arthritis (RA), Crohn’s disease, and multiple sclerosis (MS). Unlike its close relative IL-12, which promotes Th1 responses and interferon-γ (IFN-γ) production, IL-23 plays a critical role in the IL-23/Th17 axis, influencing the production of IL-17 and other pro-inflammatory cytokines that contribute to tissue inflammation
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