Interleukin 21 Receptor (IL21R) Antibody

819€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Interleukin 21 Receptor (IL21R) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx173134
tested applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Interleukin 21 Receptor (IL21R) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Purification | Purified by Protein A and Protein G affinity chromatography. |
Size 1 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Please enquire. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | NILR,CD360,IMD56,IL-21 receptor,IL-21R,Novel interleukin receptor |
Background | Antibody anti-IL21R |
Status | RUO |
Descripción
Interleukin 21 receptor (IL21R) is a member of the cytokine receptor superfamily, specifically involved in immune cell communication and regulation. IL21R binds interleukin-21 (IL-21), a cytokine that plays crucial roles in immune response modulation, primarily impacting the activity of T cells, B cells, and natural killer (NK) cells. IL-21/IL21R signaling is essential for adaptive immunity, supporting the differentiation, proliferation, and functional enhancement of immune cells. This receptor is expressed on a wide range of cells within the immune system, including T and B lymphocytes, NK cells, dendritic cells, and some epithelial cells. Given its immunoregulatory functions, IL21R signaling has implications in autoimmunity, cancer immunology, and chronic inflammatory conditions.