Category	Primary Antibodies
Immunogen Target	interleukin 21 receptor (IL21R)
Host	Rabbit
Reactivity	Human, Mouse
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality	polyclonal
Conjugation	Unconjugated
Isotype	IgG
Observed MW	68-70 kDa
Purity	≥95% as determined by SDS-PAGE
Purification	Immunogen affinity purified
Size 1	100µg
Form	liquid
Tested Applications	ELISA, WB, IHC, FC
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID	Q9HBE5
Gene ID	50615
Alias	NILR,CD360,IMD56,IL-21 receptor,IL-21R,Novel interleukin receptor
Background	Antibody anti-IL21R
Status	RUO
Note	Mol. Weight 68-70 kDa

Background

Interleukin 21 receptor (IL21R) is a member of the cytokine receptor superfamily, specifically involved in immune cell communication and regulation. IL21R binds interleukin-21 (IL-21), a cytokine that plays crucial roles in immune response modulation, primarily impacting the activity of T cells, B cells, and natural killer (NK) cells. IL-21/IL21R signaling is essential for adaptive immunity, supporting the differentiation, proliferation, and functional enhancement of immune cells. This receptor is expressed on a wide range of cells within the immune system, including T and B lymphocytes, NK cells, dendritic cells, and some epithelial cells. Given its immunoregulatory functions, IL21R signaling has implications in autoimmunity, cancer immunology, and chronic inflammatory conditions.

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