IL21R antibody

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935106861
info@markelab.com
name
IL21R antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04252
tested applications
ELISA, WB, IHC, FC
Description
This is a receptor for interleukin-21.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | interleukin 21 receptor (IL21R) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 68-70 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, FC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9HBE5 |
Gene ID | 50615 |
Alias | NILR,CD360,IMD56,IL-21 receptor,IL-21R,Novel interleukin receptor |
Background | Antibody anti-IL21R |
Status | RUO |
Note | Mol. Weight 68-70 kDa |
Descripción
Interleukin 21 receptor (IL21R) is a member of the cytokine receptor superfamily, specifically involved in immune cell communication and regulation. IL21R binds interleukin-21 (IL-21), a cytokine that plays crucial roles in immune response modulation, primarily impacting the activity of T cells, B cells, and natural killer (NK) cells. IL-21/IL21R signaling is essential for adaptive immunity, supporting the differentiation, proliferation, and functional enhancement of immune cells. This receptor is expressed on a wide range of cells within the immune system, including T and B lymphocytes, NK cells, dendritic cells, and some epithelial cells. Given its immunoregulatory functions, IL21R signaling has implications in autoimmunity, cancer immunology, and chronic inflammatory conditions.