Interleukin 21 (IL21) Antibody
377€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Interleukin 21 (IL21) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx234251
Tested Applications
ELISA, WB, IHC
Description
IL21 Antibody is a Rabbit Polyclonal against IL21.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 21 (IL21) Immunogen: interleukin 21 |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 18 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HBE4 |
| Alias | Za11,IL-21,CVID11 |
| Background | Antibody anti-IL21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 21 (IL21) is a potent cytokine produced primarily by activated CD4+ T cells, particularly T follicular helper (Tfh) cells and T helper 17 (Th17) cells. It belongs to the type I cytokine family and plays a critical role in regulating both innate and adaptive immune responses. IL-21 acts on a variety of immune cells, including B cells, T cells, natural killer (NK) cells, and dendritic cells (DCs), modulating their proliferation, differentiation, and functional activities. Its broad immunomodulatory effects make it a key regulator of immune homeostasis, inflammation, and host defense against pathogens and tumors. IL-21 is crucial for the development of germinal centers and the production of high-affinity antibodies, particularly through its regulation of B cell differentiation and antibody class switching. It also plays a significant role in promoting the cytotoxic activity of NK cells and CD8+ T cells, which are essential for anti-tumor and antiviral immunity
Productos relacionados
Interleukin 21 (IL21) Antibody
IL21 Antibody is a Rabbit Polyclonal antibody against IL21. This gene encodes a member of the common-gamma chain family …
Ver producto
Interleukin 21 (IL21) Antibody
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the pr…
Ver producto
Low Sample Volume Human Interleukin 21 (IL21) ELISA Kit
Low Sample Volume Human Interleukin 21 (IL21) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hum…
Ver producto