Interleukin 21 (IL21) Antibody
169€ (20 µl)
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Name
Interleukin 21 (IL21) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx320186
Tested Applications
ELISA, IHC
Description
IL21 Antibody is a Rabbit Polyclonal against IL21.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 21 (IL21) Immunogen: Recombinant human Interleukin-21 protein (25-162AA). |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 0.25 mg/ml |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HBE4 |
| Gene ID | 59067 |
| NCBI Accession | NP_001193935.1 |
| OMIM | 605384 |
| Alias | Za11,IL-21,CVID11 |
| Background | Antibody anti-IL21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 21 (IL21) is a potent cytokine produced primarily by activated CD4+ T cells, particularly T follicular helper (Tfh) cells and T helper 17 (Th17) cells. It belongs to the type I cytokine family and plays a critical role in regulating both innate and adaptive immune responses. IL-21 acts on a variety of immune cells, including B cells, T cells, natural killer (NK) cells, and dendritic cells (DCs), modulating their proliferation, differentiation, and functional activities. Its broad immunomodulatory effects make it a key regulator of immune homeostasis, inflammation, and host defense against pathogens and tumors. IL-21 is crucial for the development of germinal centers and the production of high-affinity antibodies, particularly through its regulation of B cell differentiation and antibody class switching. It also plays a significant role in promoting the cytotoxic activity of NK cells and CD8+ T cells, which are essential for anti-tumor and antiviral immunity
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