Interleukin 18 Binding Protein (IL18BP) Antibody

Name: Interleukin 18 Binding Protein (IL18BP) Antibody
Brand: Abbexa
SKU: abx004938
Price: 195 EUR
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

195€ (20 µl)

Antibody anti-IL18BP

proveedor

Abbexa

reference

abx004938

Tested Applications

ELISA, WB, IF/ICC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

IL18BP Antibody is a Rabbit Polyclonal antibody against IL18BP. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

Interleukin 18 Binding Protein (IL18BP)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IF/ICC

purification

Purified by affinity chromatography.

recommended dilution

ELISA: 1 µg/ml, WB: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

size 1

20 µl

size 2

100 µl

size 3

2 × 100 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

IL18BP

dry ice

availability

Shipped within 5-10 working days.

uniprot id

https://www.uniprot.org/uniprotkb/O95998

gene id

https://www.ncbi.nlm.nih.gov/gene/10068

NCBI accession

NP_001138529.1

note

Concentration: > 0.2 mg/ml -

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