Interleukin 17D (IL17D) Antibody

286€ (100 µl)
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935106861
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name
Interleukin 17D (IL17D) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129210
tested applications
WB, IHC, IF/ICC
Description
Interleukin 17D Antibody is a Rabbit Polyclonal against Interleukin 17D.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Interleukin 17D (IL17D) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q8TAD2 |
Gene ID | 53342 |
Alias | IL-17D,Interleukin-27,IL27,IL-27 |
Background | Antibody anti-IL17D |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
Interleukin 17D (IL17D) is a member of the IL-17 cytokine family, which plays a crucial role in modulating the immune response, particularly in inflammation and host defense. The IL-17 family consists of six cytokines (IL-17A through IL-17F), all of which are involved in regulating immune responses, especially those associated with infection, autoimmunity, and tissue inflammation. IL-17D is one of the less well-characterized members of this family, but it is known to have distinct roles in the regulation of innate immunity, particularly in the induction of inflammatory cytokines in various tissues. Unlike the more widely studied IL-17A and IL-17F, which are produced by Th17 cells and have well-established roles in inflammatory diseases, the function of IL-17D has only recently come to light. It is expressed in a variety of non-hematopoietic cells, including fibroblasts, endothelial cells, and smooth muscle cells, where it acts to modulate immune responses by inducing the production of inflammatory cytokines and recruiting immune cells
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