Human Interleukin 17D (IL17D) Protein
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Description
Human Interleukin 17D Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 17D (IL17D) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 45.0 kDa Observed MW (SDS-PAGE): 45 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro35-Cys169 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TAD2 |
| Gene ID | 53342 |
| Alias | IL-17D,Interleukin-27,IL27,IL-27 |
| Background | Protein IL17D |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin 17D (IL17D) is a member of the IL-17 cytokine family, which plays a crucial role in modulating the immune response, particularly in inflammation and host defense. The IL-17 family consists of six cytokines (IL-17A through IL-17F), all of which are involved in regulating immune responses, especially those associated with infection, autoimmunity, and tissue inflammation. IL-17D is one of the less well-characterized members of this family, but it is known to have distinct roles in the regulation of innate immunity, particularly in the induction of inflammatory cytokines in various tissues. Unlike the more widely studied IL-17A and IL-17F, which are produced by Th17 cells and have well-established roles in inflammatory diseases, the function of IL-17D has only recently come to light. It is expressed in a variety of non-hematopoietic cells, including fibroblasts, endothelial cells, and smooth muscle cells, where it acts to modulate immune responses by inducing the production of inflammatory cytokines and recruiting immune cells
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