Interleukin 17 Receptor C (IL17RC) Antibody
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Description
Interleukin 17 Receptor C (IL17RC) Antibody is a Rabbit polyclonal antibody for the detection of Human Interleukin 17 Receptor C (IL17RC).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 17 Receptor C (IL17RC) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NAC3 |
| Gene ID | 84818 |
| NCBI Accession | NP_001190192.1 |
| Background | Antibody anti-IL17RC |
| Status | RUO |
Descripción
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IL17RC antibody
Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495). Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F.
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Interleukin 17 Receptor C (IL17RC) Antibody
Rabbit polyclonal antibody against IL17RC protein. Immunogen region is C-terminal.
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Interleukin 17 Receptor C (IL17RC) Antibody
This gene encodes a single-pass transmembrane protein that shares limited similarity with the interleukin-17 receptor. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only three have been determined to date.
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