IL17RC antibody

IL17RC antibody
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Name
IL17RC antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab04231
Tested Applications
ELISA, WB

Description

Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495). 


Isoform 5: Receptor for both IL17A and IL17F. 


Isoform 6: Does not bind IL17A or IL17F. 


Isoform 7: Does not bind IL17A or IL17F. 


Isoform 8: Receptor for both IL17A and IL17F.

Documentos del producto

Instrucciones
Descargar
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
interleukin 17 receptor C (IL17RC)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
45-50kd
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q8NAC3
Gene ID
84818
Alias
Interleukin-17 receptor C (IL-17 receptor C, IL-17RC),Interleukin-17 receptor homolog (IL17Rhom),Interleukin-17 receptor-like protein (IL-17RL),ZcytoR14,IL17RC
Background
Antibody anti-IL17RC
Status
RUO
Note
Mol. Weight 45-50 kDa

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