IL17RC antibody
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935106861
info@markelab.com
name
IL17RC antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04231
tested applications
ELISA, WB
Description
Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495). Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interleukin 17 receptor C (IL17RC) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45-50kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8NAC3 |
| Gene ID | 84818 |
| Alias | Interleukin-17 receptor C (IL-17 receptor C, IL-17RC),Interleukin-17 receptor homolog (IL17Rhom),Interleukin-17 receptor-like protein (IL-17RL),ZcytoR14,IL17RC |
| Background | Antibody anti-IL17RC |
| Status | RUO |
| Note | Mol. Weight 45-50 kDa |
Descripción
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