Interleukin 17 Receptor A (IL17RA) Antibody (Biotin)
377€ (200 µl)
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Name
Interleukin 17 Receptor A (IL17RA) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx271424
Tested Applications
IHC
Description
Interleukin 17 Receptor A (IL17RA) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Interleukin 17 Receptor A (IL17RA).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 17 Receptor A (IL17RA) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB (Predicted): 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | IL-17 receptor A,CD217,IL17R,IMD51,CANDF5,CDw217,IL-17RA |
| Background | Antibody anti-IL17RA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin-17 receptor A (IL17RA) is a protein critical for immune responses, especially in mediating host defense against extracellular pathogens and in inflammatory processes. IL17RA is the primary receptor for the IL-17 family of cytokines, a group known to play key roles in driving immune responses by recruiting neutrophils and promoting inflammation. Among the IL-17 family, IL-17A and IL-17F are particularly significant in immune signaling via IL17RA. IL-17 cytokines and their receptors have been extensively studied for their involvement in autoimmune diseases, inflammatory conditions, and some cancers, where dysregulated IL-17 signaling leads to excessive or persistent inflammation. IL17RA, as a receptor, is broadly expressed across various cell types, including epithelial cells, fibroblasts, macrophages, and dendritic cells. This widespread expression pattern reflects the receptor’s role in both the immune and non-immune cells, enabling it to participate in the body's initial responses to infection and inflammation.
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