Interleukin 17 Receptor A (IL17RA) Antibody

Este producto es parte de IL17RA -interleukin 17 receptor A
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169€ (20 µg)

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935106861
info@markelab.com
name
Interleukin 17 Receptor A (IL17RA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx316126
tested applications
ELISA, WB, IF/ICC

Description

IL17RA Antibody is a Rabbit Polyclonal against IL17RA.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Interleukin 17 Receptor A (IL17RA)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/500 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96F46
Gene ID
23765
NCBI Accession
NP_001276834.1, NM_001289905.1, NP_055154.3, NM_014339.6
OMIM
605461
Alias
IL-17 receptor A,CD217,IL17R,IMD51,CANDF5,CDw217,IL-17RA
Background
Antibody anti-IL17RA
Status
RUO

Descripción

Interleukin-17 receptor A (IL17RA) is a protein critical for immune responses, especially in mediating host defense against extracellular pathogens and in inflammatory processes. IL17RA is the primary receptor for the IL-17 family of cytokines, a group known to play key roles in driving immune responses by recruiting neutrophils and promoting inflammation. Among the IL-17 family, IL-17A and IL-17F are particularly significant in immune signaling via IL17RA. IL-17 cytokines and their receptors have been extensively studied for their involvement in autoimmune diseases, inflammatory conditions, and some cancers, where dysregulated IL-17 signaling leads to excessive or persistent inflammation. IL17RA, as a receptor, is broadly expressed across various cell types, including epithelial cells, fibroblasts, macrophages, and dendritic cells. This widespread expression pattern reflects the receptor’s role in both the immune and non-immune cells, enabling it to participate in the body's initial responses to infection and inflammation.

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