Interleukin 15 (IL15) Antibody
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935106861
info@markelab.com
Precio
273€ (100 µl)
Antibody anti-IL15
proveedor
Abbexareference
abx101180Tested Applications
WB, IHC, IF/ICCreactivity
Rabbitstatus
RUOclonality
PolyclonalDescripción
Polyclonal Antibody to Interleukin 15 (IL15).
Background
Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Rabbit
immunogen target
Interleukin 15 (IL15)
host
Guinea pig
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by antigen-specific affinity chromatography , followed by Protein A affinity chromatography.
recommended dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
100 µl
size 2
200 µl
size 3
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IL15
dry ice
No
availability
Shipped within 5-7 working days.
alias
IL-15
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