Interleukin 15 (IL15) Antibody
637€ (100 µl)
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935106861
info@markelab.com
name
Interleukin 15 (IL15) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx113238
tested applications
ELISA, IHC
Description
Interleukin 15 Antibody is a Rabbit Polyclonal antibody against Interleukin 15.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 15 (IL15) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40933 |
| Gene ID | 3600 |
| NCBI Accession | NP_000576.1, NM_000585.4, NP_751915.1, NM_172175.2 |
| OMIM | 600554 |
| Alias | IL-15 |
| Background | Antibody anti-IL15 |
| Status | RUO |
Descripción
Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.
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