Interleukin 15 (IL-15) Antibody

Product specifications

Primary Antibodies

Interleukin 15 (IL-15)

Goat

Human

P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

200 µl

Liquid

P-ELISA, WB

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

Shipped within 5-10 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

3600

NP_000576.1, NP_751915.1

IL-15

Antibody anti-IL15

RUO

Concentration: 0.5 mg/ml -

Descripción

Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.

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