Interleukin 13 Receptor Alpha 2 (IL13Ra2) Antibody (Biotin)

Este producto es parte de IL13RA2 - interleukin 13 receptor subunit alpha 2
Interleukin 13 Receptor Alpha 2 (IL13Ra2) Antibody (Biotin)
364€ (200 µl)

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Name
Interleukin 13 Receptor Alpha 2 (IL13Ra2) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx272541
Tested Applications
WB

Description

Interleukin 13 Receptor Alpha 2 (IL13Ra2) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Interleukin 13 Receptor Alpha 2 (IL13Ra2).

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Interleukin 13 Receptor Alpha 2 (IL13Ra2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 0.5-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
200 µl
Size 2
1 ml
Form
Liquid
Tested Applications
WB
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
IL-13 receptor subunit alpha-2,CT19,IL-13R,IL13BP,CD213A2,Interleukin-13-binding protein
Background
Antibody anti-IL13RA2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Interleukin-13 receptor subunit alpha-2 (IL13RA2) is a protein encoded by the IL13RA2 gene, which functions as part of the immune system’s response to inflammation and certain immune-regulatory mechanisms. IL13RA2 is closely related to interleukin-13 receptor subunit alpha-1 (IL13RA1), both of which bind to the cytokine interleukin-13 (IL-13). However, IL13RA2 is distinctive in that it acts as a “decoy” receptor, binding IL-13 with high affinity but not actively initiating intracellular signaling, thereby modulating the effects of IL-13 on immune responses. IL13RA2 has roles in regulating allergic reactions and fibrotic processes and is often upregulated in various pathological conditions, including certain cancers. The protein's interactions with IL-13 have implications for tissue remodeling, fibrosis, and immune regulation, making it an important target in the fields of immunology, oncology, and fibrosis research.

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