Interleukin 13 Receptor Alpha 2 (IL13Ra2) Antibody
273€ (100 µl)
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935106861
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name
Interleukin 13 Receptor Alpha 2 (IL13Ra2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx103631
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Interleukin 13 Receptor Alpha 2 (IL13Ra2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 13 Receptor Alpha 2 (IL13Ra2) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O88786 |
| Alias | IL-13 receptor subunit alpha-2,CT19,IL-13R,IL13BP,CD213A2,Interleukin-13-binding protein |
| Background | Antibody anti-IL13RA2 |
| Status | RUO |
Descripción
Interleukin-13 receptor subunit alpha-2 (IL13RA2) is a protein encoded by the IL13RA2 gene, which functions as part of the immune system’s response to inflammation and certain immune-regulatory mechanisms. IL13RA2 is closely related to interleukin-13 receptor subunit alpha-1 (IL13RA1), both of which bind to the cytokine interleukin-13 (IL-13). However, IL13RA2 is distinctive in that it acts as a “decoy” receptor, binding IL-13 with high affinity but not actively initiating intracellular signaling, thereby modulating the effects of IL-13 on immune responses. IL13RA2 has roles in regulating allergic reactions and fibrotic processes and is often upregulated in various pathological conditions, including certain cancers. The protein's interactions with IL-13 have implications for tissue remodeling, fibrosis, and immune regulation, making it an important target in the fields of immunology, oncology, and fibrosis research.
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