Interleukin-12 Receptor Subunit Beta-1 (IL12RB1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Interleukin-12 Receptor Subunit Beta-1 (IL12RB1) Antibody is a Mouse Monoclonal antibody for the detection of Interleukin-12 Receptor Subunit Beta-1 (IL12RB1) in Human samples.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin-12 Receptor Subunit Beta-1 (IL12RB1) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | S266 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P42701 |
| Gene ID | 3594 |
| NCBI Accession | NP_001276952.1 |
| Alias | IL-12 receptor subunit beta-1,CD212,IMD30,IL12RB,IL-12R-BETA1,IL-12 receptor beta component |
| Background | Antibody anti-IL12RB1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
Human IL-12RB1(Interleukin-12 receptor subunit beta-1 78) ELISA Kit
Ver Producto
anti- IL12RB1 antibody
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Ver Producto
Interleukin 12 Receptor Beta 1 (IL12RB1) Antibody
IL12RB1 Antibody is a Rabbit Polyclonal antibody against IL12RB1. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
Ver Producto