Interleukin 12 Receptor Beta 2 (IL12RB2) Antibody
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Description
IL12RB2 Antibody is a Rabbit Polyclonal against IL12RB2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 12 Receptor Beta 2 (IL12RB2) |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99665 |
| Gene ID | 3595 |
| NCBI Accession | NP_001550.1 |
| Background | Antibody anti-IL12RB2 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
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IL12RB2 Antibody is a Rabbit Polyclonal against IL12RB2.
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