Interferon Omega-1 (IFNW1) Antibody
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935106861
info@markelab.com
Precio
221€ (50 µg)
Antibody anti-IFNW1
proveedor
Abbexareference
abx323555Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
IFNW1 Antibody is a Rabbit Polyclonal against IFNW1.
Background
Interferon Omega 1 (IFNW1) is a type I interferon that belongs to the family of interferons known for their critical roles in antiviral defense, immune regulation, and cell growth inhibition. IFNW1 is predominantly produced by leukocytes in response to viral infections and other immune stimuli. This cytokine binds to the type I interferon receptor (IFNAR), initiating a signaling cascade through the JAK-STAT pathway. This activation leads to the transcription of interferon-stimulated genes (ISGs), which encode proteins that inhibit viral replication, enhance antigen presentation, and activate immune cells such as natural killer cells and macrophages. IFNW1 has a similar but distinct activity profile compared to other type I interferons, such as IFN-alpha and IFN-beta, with potential applications in treating viral infections and certain malignancies. It is being explored in therapeutic contexts, including its use as an immunomodulatory agent in chronic viral infections and autoimmune disorders. Elevated levels of IFNW1 are associated with heightened immune activity, and its therapeutic modulation could provide benefits in diseases with dysregulated immune responses.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Interferon Omega-1 (IFNW1)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
size 1
50 µg
size 2
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IFNW1
dry ice
No
availability
Shipped within 5-10 working days.
alias
Interferon alpha-II-1
uniprot id
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