Interferon Induced Protein With Tetratricopeptide Repeats 2 (IFIT2) Antibody
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Description
IFIT2 Antibody is a Rabbit Polyclonal antibody against IFIT2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interferon Induced Protein With Tetratricopeptide Repeats 2 (IFIT2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P09913 |
| Background | Antibody anti-IFIT2 |
| Status | RUO |
Descripción
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Human IFIT2 (Interferon-induced protein with tetratricopeptide repeats 2) ELISA Kit
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IFIT2 antibody
IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
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Interferon Induced Protein With Tetratricopeptide Repeats 2 (IFIT2) Antibody
IFIT2 Antibody is a Rabbit Polyclonal antibody against IFIT2.
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