Interferon Alpha/Beta Receptor 2 (IFNAR2) Antibody

169€ (20 µg)
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name
Interferon Alpha/Beta Receptor 2 (IFNAR2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx301359
tested applications
ELISA, IHC
Description
IFNAR2 Antibody is a Rabbit Polyclonal against IFNAR2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interferon Alpha/Beta Receptor 2 (IFNAR2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48551 |
| Gene ID | 3455 |
| NCBI Accession | NP_000865.2, NM_000874.4, NP_001276054.1, NM_001289125.1 |
| OMIM | 602376 |
| Background | Antibody anti-IFNAR2 |
| Status | RUO |
Descripción
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IFNAR2 antibody
Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).
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