IFNAR2 antibody
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935106861
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name
IFNAR2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04148
tested applications
ELISA, WB, IF
Description
Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interferon(alpha, beta and omega) receptor 2 (IFNAR2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 58-66 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P48551 |
| Gene ID | 3455 |
| Alias | Interferon alpha/beta receptor 2 (IFN-R-2, IFN-alpha binding protein, IFN-alpha/beta receptor 2),Interferon alpha binding protein,Type I interferon receptor 2,IFNAR2,IFNABR,IFNARB |
| Background | Antibody anti-IFNAR2 |
| Status | RUO |
| Note | Mol. Weight 58-66 kDa |
Descripción
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IFNAR2 antibody
Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).
Ver Producto