Interferon Alpha 2 (IFNA2) Antibody (FITC)

169€ (20 µg)
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name
Interferon Alpha 2 (IFNA2) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx106984
Description
Interferon alpha 2 Antibody (FITC) is a Rabbit Polyclonal antibody against Interferon alpha 2 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Interferon Alpha 2 (IFNA2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | FITC |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P01563 |
Gene ID | 3440 |
OMIM | 147562 |
Alias | IFNA,leIF A,IFN-alphaA,IFN-alpha-2,Interferon alpha-A,IFNA2A,IFNA2B,IFNA2C |
Background | Antibody anti-IFNA2 |
Status | RUO |
Descripción
Interferon Alpha 2 (IFNA2) is one of the most studied type I interferons due to its significant role in antiviral defense and its clinical applications. Similar to IFNA1, IFNA2 is secreted by immune cells in response to viral infections and engages IFNAR to activate antiviral and immune-modulating pathways. IFNA2 has been extensively utilized in therapeutic settings, including recombinant IFNA2 (e.g., interferon-alpha-2a and -2b) for the treatment of viral hepatitis, certain cancers like melanoma, and hematologic malignancies. It enhances the immune system's ability to combat infections and tumors by promoting immune cell activation, increasing antigen presentation, and inducing apoptosis in infected or malignant cells. However, its use is often associated with side effects like flu-like symptoms and immune dysregulation, necessitating careful administration and monitoring.
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