Interferon alpha 14 Protein
234€ (5 µg)
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name
Interferon alpha 14 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx260707
tested applications
SDS-PAGE
Description
Interferon-alpha 14 Protein is a recombinant cytokine.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | IFNA14 |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P01570 |
| Alias | LEIF2H,IFN-alphaH,FN-alpha-14,Interferon lambda-2-H,Interferon alpha-H,LeIF H |
| Background | Protein IFNA14 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interferon Alpha 14 (IFNA14) is an integral member of the type I interferon family and contributes significantly to the immune system's antiviral defense. Like other alpha interferons, IFNA14 is secreted by plasmacytoid dendritic cells, monocytes, and other immune cells in response to viral infections, particularly during the early stages. Once released, IFNA14 binds to the interferon alpha/beta receptor (IFNAR) on the surface of various cell types, initiating a signaling cascade through the JAK-STAT pathway. This leads to the transcription of numerous interferon-stimulated genes, which are crucial for antiviral activities, such as halting viral replication, promoting apoptosis in infected cells, and enhancing antigen presentation to T cells. Furthermore, IFNA14 aids in the activation and proliferation of natural killer (NK) cells and cytotoxic T lymphocytes, strengthening the immune system's ability to target and eliminate infected cells. Its specific role within the alpha interferon family may involve unique expression patterns or targeted immune functions, though further research is needed to fully delineate its contributions to immunity and potential clinical applications.
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