Interferon Alpha 14 (IFNA14) Antibody (FITC)
169€ (20 µg)
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name
Interferon Alpha 14 (IFNA14) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx106986
Description
Interferon alpha-14 Antibody (FITC) is a Rabbit Polyclonal antibody against Interferon alpha-14 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interferon Alpha 14 (IFNA14) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01570 |
| Gene ID | 3448 |
| OMIM | 147579 |
| Alias | LEIF2H,IFN-alphaH,FN-alpha-14,Interferon lambda-2-H,Interferon alpha-H,LeIF H |
| Background | Antibody anti-IFNA14 |
| Status | RUO |
Descripción
Interferon Alpha 14 (IFNA14) is an integral member of the type I interferon family and contributes significantly to the immune system's antiviral defense. Like other alpha interferons, IFNA14 is secreted by plasmacytoid dendritic cells, monocytes, and other immune cells in response to viral infections, particularly during the early stages. Once released, IFNA14 binds to the interferon alpha/beta receptor (IFNAR) on the surface of various cell types, initiating a signaling cascade through the JAK-STAT pathway. This leads to the transcription of numerous interferon-stimulated genes, which are crucial for antiviral activities, such as halting viral replication, promoting apoptosis in infected cells, and enhancing antigen presentation to T cells. Furthermore, IFNA14 aids in the activation and proliferation of natural killer (NK) cells and cytotoxic T lymphocytes, strengthening the immune system's ability to target and eliminate infected cells. Its specific role within the alpha interferon family may involve unique expression patterns or targeted immune functions, though further research is needed to fully delineate its contributions to immunity and potential clinical applications.
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