Intercellular Adhesion Molecule 3 (ICAM3) Antibody (FITC)
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Intercellular Adhesion Molecule 3 (ICAM3) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx343567
Description
Intercellular Adhesion Molecule 3 (ICAM3) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human ICAM3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Intercellular Adhesion Molecule 3 (ICAM3) Immunogen: Recombinant Human Intercellular adhesion molecule 3 protein (200-547 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32942 |
| Alias | CD50,CDW50,ICAM-R,Intercellular adhesion molecule 3 |
| Background | Antibody anti-ICAM3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Intercellular Adhesion Molecule 3 (ICAM3), also known as CD50, is a member of the immunoglobulin superfamily (IgSF) that plays a crucial role in cell-cell adhesion and immune system regulation. It is expressed predominantly on leukocytes, especially resting lymphocytes, and interacts with integrins to mediate various immune responses, including leukocyte trafficking, T-cell activation, and antigen recognition. ICAM3 is particularly involved in the early stages of immune responses, functioning as a ligand for leukocyte function-associated antigen-1 (LFA-1), an integrin found on T cells and other leukocytes. ICAM-3 acts as a facilitator of immunological synapse formation, helping leukocytes adhere to antigen-presenting cells and promoting signaling pathways critical for immune activation. Its interaction with integrins also promotes adhesion between leukocytes and endothelial cells, an important step in the migration of immune cells to sites of inflammation or infection. ICAM-3 is essential in regulating leukocyte dynamics and activation during immune surveillance and host defense.
Productos relacionados
Intercellular Adhesion Molecule 3 (ICAM3) Antibody
ICAM3 Antibody is a Rabbit Polyclonal antibody against ICAM3. The protein encoded by this gene is a member of the interc…
Ver producto
Human Intercellular Adhesion Molecule 3 (ICAM3) Protein
Human Intercellular Adhesion Molecule 3 Protein is a recombinant Human protein expressed in E. coli.…
Ver producto
Intercellular Adhesion Molecule 3 (ICAM3) Antibody
Intercellular Adhesion Molecule 3 is a Rabbit Polyclonal against Intercellular Adhesion Molecule 3.…
Ver producto