Intercellular Adhesion Molecule-2 Protein

Este producto es parte de ICAM2 - intercellular adhesion molecule 2
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234€ (2 µg)

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935106861
info@markelab.com
name
Intercellular Adhesion Molecule-2 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262761
tested applications
SDS-PAGE

Description

ICAM2 is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetICAM2
ConjugationUnconjugated
ExpressionRecombinant
Purity> 90% (SDS-PAGE)
Size 12 µg
Size 210 µg
Size 31 mg
FormLiquid
Tested ApplicationsSDS-PAGE
AvailabilityShipped within 5-10 working days.
Dry IceNo
UniProt IDP13598
AliasIntercellular adhesion molecule 2,CD102,ICAM-2
BackgroundProtein ICAM2
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Intercellular adhesion molecule 2 (ICAM2) is a member of the immunoglobulin superfamily and plays an essential role in immune cell trafficking, endothelial integrity, and cell signaling. ICAM-2 is encoded by the ICAM2 gene and, along with other intercellular adhesion molecules, serves as a ligand for leukocyte integrins such as LFA-1 (lymphocyte function-associated antigen-1), facilitating the adhesion and transmigration of leukocytes across endothelial cells. It is broadly expressed on endothelial cells, leukocytes, and various other cell types. ICAM-2 is involved in vascular and immune system homeostasis, with roles extending to inflammation, cancer, and neurological functions. Unlike ICAM-1, which is inducible by inflammatory cytokines, ICAM-2 is constitutively expressed but has been found to increase in certain pathophysiological conditions, especially involving endothelial activation. The stable presence of ICAM-2 on endothelial cells makes it significant for lymphocyte recirculation and endothelial-leukocyte interactions, aiding immune surveillance and response to pathogens.
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